What is Paget’s Disease of Bone?

Paget’s Disease, or osteitis deformans as Sir James Paget described
it in 1877, is a chronic bone disorder which occurs when the normal process of bone remodelling goes out of control, resulting in the formation of new abnormally structured bone. Excessive bone breakdown and formation makes bone dense but fragile. These processes may occur in one or many parts of the skeleton and can result in weakened, enlarged or misshapen bones, which may be painful, press on neighbouring nerves or fracture easily. Enlargement of the skull with varying degrees of deafness is common and when the long bones of the leg are involved, bowing deformity may occur. Joints also become involved because of the unequal stresses imposed by the bent bones. It is usually a very slowly progressive disorder.

Paget’s Disease – some facts

  • 1 in 20 of the older population of this country suffers from Paget’s disease.
  • In some areas this can be as high as 1 in 12 of people over the age of 40!
  • Paget’s disease is a severe, crippling bone disease for which there is no cure and no known cause.
  • Paget’s disease was discovered in the UK during Queen Victoria’s reign and we can boast to having many of the world’s leading doctors and scientific experts, but their hands are tied.
  • In the USA, millions of dollars are being invested by the government on research into Paget’s disease.
  • The UK government has no programme for funding Paget’s disease research.

Information Courtesy of:
The National Association for the Relief of Pagets Disease
323 Manchester Road,
Walkden,
Worsley,
Manchester,
M28 3HH

Tel. No: 0161 7994646
Fax No: 0161 7996511
Email: director@paget.org.uk

For Further information visit the website
www.paget.org.uk

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